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My research interest is Embryonic Stem Cells (ES cells) in chimeric mouse models. Concentrating on which Green Fluorescent Protein (GFP) variants will give the best quantitative results and distinguish donor, recipient and hybrid transgene expression in ES cell allographs implanted into hypoxic host neural tissues. The overall purpose of the research is to determine how to prevent apoptosis (programmed cell death) in neurodegenerative diseases. Applications include developing novel therapeutic approaches for treating stroke, Alzheimer’s, and Parkinson’s diseases. There also are potential applications relevant to the plasticity in adult stem cells versus embryonic stem cells. These applications could impact the debate concerning transdifferentiation i.e. the ability of designated stem cells to differentiate into unrelated cells in the right environment negating the necessity of embryonic donors. Click here to see research images.
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| Access to Models for BI204 and BI205 Link for models of Bones chapters 6-7 and Muscles chapters 8-10 Link for clear definitions for all major medical and lab tests with clinical implications: |
| BI205 Objectives | |
| The following files are in MS Word format. | |
| Blood Vessels | |
| Blood | |
| Lymphatic/Immune | |
| Digestive | |
| Reproduction | |
| Respiration | |
| Urinary | |
| Endocrine | |
| Heart | |
| Developing a College and Work Portfolio Science Lab Report Form
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| Page Created by: Jason Fuller Updated: April 21 2009 | Biology Department Science North, Room 211 7600 Takoma Avenue, Takoma Park, MD 20912 Phone: 240-567-1422 Fax: 240-567-1410 |